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Calkins is responsible for policy and strategy development and strategic implementation of all EH&S and sustainability programs at Xerox worldwide. A pioneer in environmental management, Xerox saves hundreds of millions of dollars annually through its initiatives. Its goal of "waste-free products from waste-free factories" filters through all aspects of the company's operations -- from designing products, processes and facilities to capture energy savings, to creating printers and copiers that can be remanufactured, to making recyclable toner cartridges, and much more. Calkins joined Xerox as a manager of resource conservation in 1993 and then assumed increasingly responsible management positions in quality and business process, EH&S market support, and Design for Lean Six Sigma programs in the Xerox Engineering Center. She most recently served as vice president, EH&S Operations.

Calkins is a member of the external advisory board for the University of Michigan's Center for Sustainable Systems and a member of the board of trustees for the Nature Conservancy Central and Western New York Chapter. From 1997-2002 she was chair for the Institute of Electrical and Electronics Engineers Computer Society Technical Committee on electronics and the environment; and from 1994-1997 she served as chair for the Information Technology Industry Council Technical Committee on product life-cycle environmental management. She is also a past member of the advisory board at the University of Massachusetts Toxics Use Reduction Institute and of the advisory committee at the Massachusetts Department of Environmental Protection.

Calkins received a bachelor of arts degree in biology in 1979 from Merrimack College, North Andover, Mass. She earned her master of science degree in civil/ environmental engineering at Tufts University in 1991, and in 2001 received her Executive MBA from the University of Rochester.